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Pharmacelsus

Services for Biologics

The services for biologics cover the characterisation of biological therapeutics like antibodies, ADCs, proteins or peptides. Support for the development of bioanalytical methods with mass spectrometric detection on request.

Equipment

  • QTOF X500B
  • Software:
    • SCIEX V.1.6
    • BioPharmaViewTM / BioPharmaFlexTM
    • ProteinPilotTM

Intact analysis / subunit analysis

  • MW determination and distribution
  • Drug-to antibody ratio
  • Purity
  • Aggregation
  • Stability in biological matrixes
  • Post-translational modifications
  • Glycan pattern
  • Qualitative Batch comparison

Peptide analysis

  • Confirmation of Amino acid sequence
  • Identification of N and C-Termini
  • Stresssudies (Oxidation, Deamidation)
  • S-S bridges determination
  • Purity
  • Qualitative Batch comparison
  • Proteinogenic impurities
Download Pharmacelsus Documents

Characterization of Biopharmaceuticals

Please contact us for your specific biological study!

MUDr. Maria Li
Director Business Development
li@pharmacelsus.de

Dr. Catharina Steffen
Project Manager Bioanalytics
steffen@pharmacelsus.de