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Pharmacelsus

In vitro & in vivo Pharmacology Services

To gain profound and relevant preclinical data on efficacy and potency, in-depth knowledge of the corresponding disease is a key success factor. Pharmacelsus has a proven track record on conducting in vitro and in vivo studies on potency, selectivity and efficacy in several indication areas.

In vitro pharmocology assays

5α Reductase Inhibitors

  • Human recombinant isoenzymes type I and II

In vivo pharmocology models

Diabetes / Metabolic Syndrome Models

  • Induced Models:
    • STZ Mice/Rats
    • DIO Mice/Rat
  • Genetic Models:
    • ob/ob Mice
    • db/db Mice
    • Zucker/ZDF Rat

Cancer

  • In vivo model
    (immunodeficient mice)
  • Principle:
    s.c. tumor xenograft model
  • General Readouts:
    Tumor incidence, tumor size, tumor growth inhibition, terminal tumor weight, Occurence of metastases (postmortal)

Leveraging our experience allows us to design, set-up and perform in vitro and in vivo pharmacology studies according to the specific requirements of your project.

Please contact us for your specific pharmacology study!

Dr. Julia Przibilla
Team Manager ADMET and in vitro Pharmacology
przibilla@pharmacelsus.de

Anika Christoffel
Team Manager in vivo Pharmacology & Pharmacokinetic
christoffel@pharmacelsus.de

Pharmacelsus GmbH
Science Park 2
66123 Saarbruecken / Germany

Phone: +49 (0)681 3946 7510
Email:  info@pharmacelsus.de